Merkel Cell Carcinoma (MCC): A Rare Form of Skin Cancer

Merkel cell carcinoma (MCC) is an uncommon yet highly aggressive skin cancer that poses a significant risk of recurrence and metastasis, often within two to three years following initial diagnosis.

THE RARITY OF MCC:

Approximately 3,000 new MCC cases are diagnosed annually in the United States, and this number is projected to rise to 3,250 cases by 2025. In comparison, MCC is 40 times rarer than melanoma, affecting approximately one individual per 130,000 in the U.S.

RISK FACTORS:

MCC risk factors include sun exposure, fair skin, age over 50, and a weakened immune system.

JIMMY BUFFETT's BATTLE:

Renowned singer-songwriter Jimmy Buffett confronted MCC for four years before his passing on September 1, 2023. Throughout his battle, he continued to perform, showcasing incredible resilience.

WHAT ARE MERKEL CELLS?

Merkel cells, situated deep within the skin's top layer, are associated with nerve receptors responsible for touch sensation. MCC was named after Merkel cells due to certain microscopic similarities, although recent research suggests a distinct origin.

IDENTIFYING MCC

MCC tumors frequently manifest in sun-exposed areas but lack distinct characteristics typical of other skin cancers. They can resemble pearly, pimple-like lumps, varying in color from skin-toned to red, purple, or bluish-red. Remarkably, they are rarely tender to the touch. Their rapid growth often attracts both patient and physician attention.

MCC's SEVERITY:

While MCC is three to five times more likely to be fatal than melanoma, early detection greatly improves treatment outcomes. Seeking medical evaluation if you suspect MCC is crucial, as treatment becomes progressively challenging once the disease advances. Fortunately, recent advances in immunotherapy have led to improved survival rates for MCC patients.

If you notice any new, changing, or unusual skin issues, please schedule an appointment with us here.